Failure prediction of metastatic bone with osteolytic lesion in mice
DELPUECH ; NICOLLE ; CONFAVREUX ; BOUAZZA ; CLEZARDIN ; FOLLET ; MITTON
Type de document
COMMUNICATION AVEC ACTES INTERNATIONAL (ACTI)
Langue
anglais
Auteur
DELPUECH ; NICOLLE ; CONFAVREUX ; BOUAZZA ; CLEZARDIN ; FOLLET ; MITTON
Résumé / Abstract
Metastatic cancer affects the skeleton. Bone metastases weaken bones, and physicians have to decide the emergency of a surgical intervention. Current tools do not allow an accurate prediction of metastatic bone failure. Recent studies showed that patient-specific finite element analysis (FEA) could contribute to improve this diagnosis). However, in those studies, limitations were underlined in their discussion (e.g. boundary conditions and mechanical properties of tumoral tissues). The aim of this study was to use an animal model for a deeper understanding of key factors in FE modelling.
