Energy Deregulation Precedes Alteration in Heart Energy Balance in Young Spontaneously Hypertensive Rats: A Non Invasive In Vivo 31P-MR Spectroscopy Follow-Up Study

DESCHODT-ARSAC ; ARSAC ; MAGAT ; NAULIN ; QUESSON ; DOS SANTOS ; CHEN

Type de document
ARTICLE A COMITE DE LECTURE REPERTORIE DANS BDI (ACL)
Langue
anglais
Auteur
DESCHODT-ARSAC ; ARSAC ; MAGAT ; NAULIN ; QUESSON ; DOS SANTOS ; CHEN
Résumé / Abstract
Gradual alterations in cardiac energy balance, as assessed by the myocardial PCr/ATP-ratio, are frequently associated with the development of cardiac disease. Despite great interest for the follow-up of myocardial PCr and ATP content, cardiac MR-spectroscopy in rat models in vivo is challenged by sensitivity issues and cross-contamination from other organs.
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